GEN-RWD Sandbox: bridging the gap between hospital data privacy and external research insights with distributed analytics

Table 1 Interactions of each GEN-RWD Sandbox module with the Proxy

Module	Functionality	From Proxy	To Proxy
GUI	User Authentication	• Authentication Response	• Authentication Request and ACK^a
	Job Submission	• Job’s queued ACK^a	• Job Request
	Job Outputs’ Presentation	• Job’s logs and outputs
	Platform monitoring	• Number of available processor info Response	• Number of Available Processors Info Request
	Platform monitoring	• Algorithm and Datamart Metadata Update Info Response	• Algorithm and Datamart Metadata Update Info Request
permAgent	User Authentication	• Credential Verification Request	• Credential Verification Response
permAgent	User Permission Verification	• Permission Verification Request	• Permission Verification Response
Scheduler	Job Scheduling	• Scheduling Request	• Periodic Task Trigger
B &C Agent^b	Job Notarization	• Job’s Notarization Request	• Job’s Notarization Results
B &C Agent^b	Job’s Output Signature	• Digital Signature Request	• Digitally signed Outputs
Processor	Job Execution	• Job execution details	• Job’s logs and outputs

ISSN: 1472-6947