Table 1 Baseline demographic, clinical, and biological characteristics of patients who progressed to diabetic kidney disease and those who did not
Characteristics | DKD (N = 563) | Non-DKD (N = 2728) | p-value |
|---|---|---|---|
Demographics (N = 2) |  |  |  |
Age | 66 (54–75) | 60 (50–68) | < 0.001 |
Gender | Â | Â | 0.413 |
 Female | 256 | 1295 |  |
 Male | 307 | 1433 |  |
Lifestyle (N = 2) |  |  |  |
 is_drinking | 62 (11.01%) | 360 (13.20%) | 0.180 |
 is_smoking | 106 (18.83%) | 518 (18.99%) | 0.977 |
Blood routine (N = 21) |  |  |  |
 WBC_Cnt | 6.1 (5.1–7.8) | 6.3 (5.2–7.7) | 0.495 |
 Neut_Cnt | 3.8 (2.9–5.1) | 3.8 (2.9–5) | 0.724 |
 Hct | 39.4 (36–42.6) | 40.5 (37.5–43.9) | < 0.001 |
 Hb | 133 (121–145) | 137.5 (127–150) | < 0.001 |
 Lymph_Per | 27.3 (20.9–33.55) | 29.2 (22.6–35.6) | < 0.001 |
 Baso_Cnt | 0.02 (0–0.03) | 0.02 (0.01–0.03) | < 0.001 |
 RBC_Cnt | 4.26 (3.89–4.71) | 4.44 (4.10–4.85) | < 0.001 |
 MCV | 91.9 (88.9–95.1) | 91.2 (88.48–93.8) | < 0.001 |
 Lymph_Cnt | 1.6 (1.3–2.1) | 1.8 (1.4–2.2) | < 0.001 |
 MCH | 31.1 (29.8–32.3) | 31 (30–32) | 0.436 |
 Neut_Per | 62.8 (56–70.15) | 61.7 (54.7–68.6) | 0.049 |
 Mono_Cnt | 0.4 (0.3–0.5) | 0.4 (0.3–0.5) | 0.001 |
 Mono_Per | 6.8 (5.5–8.1) | 6.1 (5.1–7.5) | < 0.001 |
 PDW | 16.5 (16.2–16.9) | 16.4 (16.1–16.7) | < 0.001 |
 Eos_Per | 1.8 (0.9–3) | 1.6 (0.9–2.7) | 0.104 |
 PLTHct | 0.19 (0.15–0.22) | 0.2 (0.16–0.23) | < 0.001 |
 MCHC | 338 (332.75–343.25) | 340 (334–346) | < 0.001 |
 PLT_Cnt | 190 (154–230) | 198.75 (163–239.6) | < 0.001 |
 MPV | 9.8 (9.1–10.75) | 9.8 (9–10.7) | 0.632 |
 Baso_Per | 0.4 (0.3–0.6) | 0.4 (0.3–0.6) | 0.454 |
 RDWCV | 13 (12.6–13.5) | 12.8 (12.4–13.4) | < 0.001 |
Biochemical analysis (N = 13) |  |  |  |
 LDL | 2.27 (1.75–2.76) | 2.45 (1.91–3.01) | < 0.001 |
 TC | 4.34 (3.7–5.09) | 4.58 (3.86–5.27) | < 0.001 |
 Crea | 61 (51–73) | 59 (49.875–69) | < 0.001 |
 HbA1c | 7.6 (6.5–9.6) | 7.4 (6.5–9) | 0.118 |
 HDL | 1.13 (0.9–1.355) | 1.185 (0.99–1.43) | < 0.001 |
 TBIL | 10.5 (7.65–14) | 11.1 (8.3–15) | < 0.001 |
 PA | 236.9 (192.65–286.55) | 242.8 (196.675–291.225) | 0.248 |
 TG | 1.43 (1.055–2.06) | 1.44 (1.02–2.1) | 0.838 |
 ALT | 19 (13–29) | 21 (14–32) | < 0.001 |
 AST | 19 (16–27) | 20 (16–27) | 0.966 |
 ASTALT | 1 (0.8–1.4) | 0.9 (0.7–1.2) | < 0.001 |
 Ca | 2.23 (2.13–2.32) | 2.25 (2.16–2.34) | < 0.001 |
 Eos_Cnt | 0.1 (0.06–0.2) | 0.1 (0.05–0.17) | 0.124 |
Urinalysis (N = 7) |  |  |  |
 pH | 6.5 (6–7) | 6 (5.5–6.5) | < 0.001 |
 glu_qual | 204 (36.23%) | 1058 (38.78%) | 0.278 |
 ket_qual | 47 (8.35%) | 299 (10.96%) | 0.078 |
 uro_qual | 6 (1.07%) | 23 (0.843%) | 0.790 |
 nit_qual | 15 (2.66%) | 48 (1.76%) | 0.209 |
 ob_qual | 69 (12.26%) | 287 (10.52%) | 0.257 |
 bil_qual | 3 (0.533%) | 8 (0.293%) | 0.620 |
Blood coagulation function (N = 1) |  |  |  |
 DDimer | 133 (78–268.5) | 105 (61.75–202) | < 0.001 |