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Table 1 Comparison of clinical data between non-fungal infection group and fungal infection group

From: Development of machine learning models to predict the risk of fungal infection following flexible ureteroscopy lithotripsy

Variable

Non-fungal infection group N = 3976

Fungal infection group N = 178

χ²/Z

P

General data

    

Age (M (P25,P75), years)

50.0 (38.0,59.0)

59.0 (49.0,67.0)

−7.154

<0.001*

Female (n (%))

1571 (39.5)

106 (59.6)

28.419

<0.001*

BMI (M (P25,P75), kg/m²)

24.8(22.8,27.7)

25.1(22.2,27.4)

−0.06

0.996

DM (n (%))

581 (14.6)

67 (37.6)

71.879

<0.001*

History of malignancy (n (%))

240 (6.0)

64 (36.0)

224.847

<0.001*

Being bedridden (n (%))

95 (2.4)

34 (19.1)

158.133

<0.001*

Immunosuppression (n (%))

26 (0.7)

12 (6.7)

63.104

<0.001*

Preoperative data

    

Admission HB (M (P25,P75), g/L)

129.0 (117.0, 143.0)

129.0 (116.8, 140.0)

−1.483

0.138

Admission WBC (M (P25,P75),*109/L)

6.6 (5.1, 8.7)

7.6 (5.7, 10.1)

−4.153

<0.001*

Admission Neu (M (P25,P75),*109/L)

4.1 (3.0, 5.6)

4.7 (3.3, 7.3)

−3.197

0.001*

Admission ALB <30 g/L (n (%))

79 (2.0)

13 (7.3)

19.848

<0.001*

Admission ALT (M (P25,P75),U/L)

19.0(13.0, 29.8)

17.0(12.0, 28.3)

−1.397

0.162

Admission AST (M (P25,P75),U/L)

15.0(11.0,19.0)

13.0(8.0, 22.0)

−1.854

0.064

Admission Scr (M (P25,P75),μmoI/L)

74.0 (63.0, 92.0)

74.0 (55.0, 107.3)

−0.576

0.565

Pyuria (n (%))

3234 (81.3)

157 (88.2)

5.354

0.021*

Urinary nitrite (n (%))

129 (3.2)

17 (9.6)

19.979

<0.001*

Urine pH (M (P25,P75))

6.5 (6.0,7.0)

6.5 (6.0, 6.5)

−0.381

0.703

Multiple stones (n (%))

1886 (47.4)

90 (50.6)

0.668

0.414

Maximum stone diameter (M (P25,P75), mm)

10.8 (7.5, 16.5)

10.4 (8.0, 15.3)

−0.410

0.682

PSD (M (P25,P75), HU)

1275.0 (980.0, 1463.0)

1290.5 (1007.0, 1408.0)

−1.393

0.164

SFU grading (n (%))

  

7.559

0.109

0

644 (16.2)

18 (10.1)

  

I

805 (20.2)

35 (19.7)

  

II

1003 (25.2)

50 (28.1)

  

III

1188 (29.9)

53 (29.8)

  

IV

336 (8.5)

22 (12.4)

  

Ureteral Stenting (n (%))

584(14.7)

59(33.1)

44.367

<0.001*

PNS (n (%))

34(0.9)

6(3.4)

11.306

0.006*

Intraoperative data

    

Operation time (M (P25,P75), min)

53.0(31.0, 75.0)

70.0 (50.0, 111.3)

−6.849

<0.001*

UAS (n (%))

  

6.191

0.013*

T-UAS

3801(95.6)

177(99.4)

  

NP-UAS

175(4.4)

1(0.6)

  

Postoperative data

    

Fever (n (%))

890 (22.4)

110 (61.8)

149.797

<0.001*

Postoperative WBC (M (P25,P75),*109/L)

7.0 (5.3, 9.2)

7.4 (6.2, 10.1)

−3.338

0.001*

Postoperative Neu (M (P25,P75),*109/L)

5.1 (3.2, 7.1)

6.1 (4.5,8.2)

−5.702

<0.001*

Postoperative Ca (M (P25,P75), mmol/L)

2.3 (2.3, 2.4)

2.3 (2.3,2.4)

−0.744

0.457

CSRF (n (%))

1416(35.6)

73(41.0)

2.158

0.142

Infectious stones (n (%))

1149 (28.9)

54 (30.3)

0.171

0.679

Urethral catheterization duration (M (P25,P75), days)

1.0 (1.0,4.0)

2.0 (1.0,4.0)

−4.105

<0.001*

Stent duration (M (P25,P75), weeks)

4.0 (4.0,8.0)

8.0 (4.0,12.0)

−7.832

<0.001*

Other data

    

Carbapenem antibiotics use (n (%))

252 (6.3)

94 (52.8)

481.863

<0.001*

Duration of antibiotic therapy (M (P25,P75), days)

4.0 (3.0, 6.0)

8.0 (6.0, 9.0)

−14.565

<0.001*

LOS (M (P25,P75), days)

6.0 (4.0, 8.0)

12.0 (7.0, 14.0)

−13.616

<0.001*

  1. BMI body mass index, DM diabetes mellitus, Immunosuppression long-term immunosuppressive therapy, HB hemoglobin, WBC white blood cells, Neu neutrophils, ALT alanine transaminase, AST aspartate transaminase, Scr serum creatinine, PSD peak stone density, PNS percutaneous nephrostomy, UAS ureteral access sheath, T-UAS traditional ureteral access sheath, NP-UAS negative-pressure ureteral access sheath, Ca serum calcium, CSRF clinically significant residual fragments, LOS length of hospital stay